Blázquez Fernández, AitorMarcos Antón, SelenaEstrada Barranco, CeciliaMartín Casas, PatriciaOrtiz Gutiérrez, Rosa MaríaJiménez Antona, CarmenLaguarta Val, SofíaCano de la Cuerda, Roberto2026-10-192026-10-192026Blázquez-Fernández A, Marcos-Antón S, Estrada-Barranco C, Martín-Casas P, Ortiz-Gutiérrez RM, Jiménez-Antona C, Laguarta-Val S, Cano-de-la-Cuerda R. Early Upper Limb Motor Impairment in Multiple Sclerosis Across EDSS Levels: A Case-Control Study. Brain Behav. 2026 Aug;16(8):e71529. doi: 10.1002/brb3.71529IF: 2.8 Q2 . PMID: 42533673; PMCID: PMC13425605.2162-3279https://hdl.handle.net/11268/17499Upper limb (UL) involvement is common from the early stages in people with multiple sclerosis (PwMS) and has a significant impact on daily activities, quality of life, and autonomy. However, it may be underestimated by the Expanded Disability Status Scale (EDSS). The objective of this study was to determine differences in UL function between PwMS, stratified by EDSS ≤3.5 and >3.5, and healthy controls (HCs), as well as between PwMS subgroups according to EDSS score.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/FisioterapiaEsclerosis MúltipleExtremidad SuperiorDestreza Motorajournal article10.1002/brb3.71529open accessNeurologíaRehabilitación médicaCalidad de vidaGoal 3: Ensure healthy lives and promote well-being for all at all agesGoal 10: Reduce inequality within and among countries