Neu, Marie AstridDreismickenbecker, EliasLanfranconi, FrancescaStössel, SandraBalduzzi, AdrianaWright, PeterWindsor, StanWiskemann, JoachimLucía Mulas, AlejandroFiuza Luces, María del Carmenet al.2026-07-312026-07-312025Neu, M. A., Dreismickenbecker, E., Lanfranconi, F., Stössel, S., Balduzzi, A., Wright, P., Windsor, S., Wiskemann, J., El-Rajab, I., Lucia, A., Fiuza-Luces, C., Mongondry, R., Fridh, M. K., Spreafico, F., Konda, B., Kitanovski, L., Heißerer, B., Polak, M., Baader, T., … Diel, H. (2025). Get strong to fight childhood cancer - an exercise intervention for children and adolescents undergoing anti-cancer treatment (Fortee): Rationale and design of a randomized controlled exercise trial. BMC Cancer, 25(1), 1275. https://doi.org/10.1186/s12885-025-14489-y1471-2407https://hdl.handle.net/11268/17352Despite substantial advances in treatment, children and adolescents with cancer continue to face high morbidity and health issues, including cancer-related fatigue, treatment-related complications, and physical inactivity. Integrating exercise into pediatric oncology care has emerged as a promising approach to mitigate these burdens during cancer treatment. While preliminary data support its potential to reduce treatment-related side effects and enhance quality of life, robust evidence -especially from large, multicenter trials- remains limited. As a progress beyond the current state-of-the-art, FORTEe has the ambition to implement pediatric exercise oncology as an evidence-based treatment option for all childhood cancer patients, ultimately integrating it as a standard into clinical practice worldwide.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/Ciencias del DeporteNeoplasiasTerapia por EjercicioEnsayo Clínico Aleatorizadojournal article10.1186/S12885-025-14489-Yopen accessCiencias médicasCáncerPediatríaGoal 3: Ensure healthy lives and promote well-being for all at all agesGoal 10: Reduce inequality within and among countries