Demnitz-King, HarrietAdeleke, MariamBarber, JuliePoppe, MichaelaBudgett, JessicaAlberts, SweedalDuffy, LarisaMinihane, Anne-MarieGillings, RachelAguirre Sánchez, Elisaet al.2025-11-182025-11-182025Demnitz-King, H., Adeleke, M., Barber, J. A., Poppe, M., Budgett, J., Alberts, S., Duffy, L., Minihane, A.-M., Gillings, R., Chapman, H., Espinoza Jeraldo, R. I., Kelsey, O., Muralidhar, M., Zabihi, S., Aguirre, E., Bass, N., Betz, A., Brodaty, H., Burton, A., … Cooper, C. (2025). Remote, lower-intensity, multidomain lifestyle intervention for subjective cognitive decline or mild cognitive impairment (Apple-tree): A multicentre, single-masked, randomised controlled trial. The Lancet Healthy Longevity, 6(10), 100777. https://doi.org/10.1016/j.lanhl.2025.1007772666-7568https://hdl.handle.net/11268/16487Trials of high-intensity, multidomain interventions show that modifying lifestyle and psychological risk factors can slow cognitive decline. We aimed to evaluate the effectiveness of a lower-intensity, personally-tailored dementia prevention programme in improving cognition in adults with subjective cognitive decline or mild cognitive impairment.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal article10.1016/j.lanhl.2025.100777open accessCiencias médicasMedicina preventivaGerontologíaGoal 3: Ensure healthy lives and promote well-being for all at all agesGoal 4: Quality educationGoal 10: Reduce inequality within and among countries