Fabrication of heterogeneous biocatalyst tethering artificial prosthetic groups to obtain omega-3-fatty acids by selective hydrolysis of fish oils

Moreno Pérez, Sonia2017-01-052017-01-052016Moreno-Pérez, S., Fernández-Lorente, G., Romero, O., Guisán, J. M., & López-Gallego, F. (2016). Fabrication of heterogeneous biocatalyst tethering artificial prosthetic groups to obtain omega-3-fatty acids by selective hydrolysis of fish oils. RSC Advances, 6(100), 97659-97663.20462069http://hdl.handle.net/11268/6139The active site of lipase from Bacillus thermocathenolatus was selectively modified with allyl and naphthyl chains at different positions. Lipase immobilization and selective tethering of a naphthyl side chain to its position 320 improve both the hydrolysis rate of fish oils and the selectivity towards the eicosapentaenoic acid acyl chains. © The Royal Society of Chemistry 2016.engOmega-3-fatty acidsProsthetic groupsFabrication of heterogeneous biocatalyst tethering artificial prosthetic groups to obtain omega-3-fatty acids by selective hydrolysis of fish oilsjournal article10.1039/c6ra21121frestricted accessIngeniería BiomédicaBiotecnología