Rubia Ortí, José Enrique de laSancho Castillo, SandraBenlloch, MaríaJulián Rochina, MarianoCorchón Arreche, SilviaGarcía Pardo, María Pilar2020-03-122020-03-122017de la Rubia Ortí, J. E., Sancho Castillo, S., Benlloch, M., Julián Rochina, M., Corchón Arreche, S., & García-Pardo, M. P. (2016). Impact of the Relationship of Stress and the Immune System in the Appearance of Alzheimer’s Disease. Journal of Alzheimer’s Disease, 55(3), 899–903. https://doi.org/10.3233/JAD-1609031387-2877http://hdl.handle.net/11268/8756The understanding of how the immune system works, as well as its relationship with the stress level, seems to be important at the start of the Alzheimer’s disease (AD). To analyze this, immunoglobulin A (IgA) and cortisol in saliva were measured using ELISA in patients with mild AD and healthy volunteers, and the production of both biomarkers was compared and correlated. In participants without AD, IgA was higher when cortisol was lower, and the opposite happened in participants with AD, with the quantification in saliva being a suitable method to determine it.engjournal article10.3233/JAD-160903restricted accessEnfermedad de AlzheimerEstrésEfectos fisiológicosEnfermedad del sistema nerviosoEstrés mentalEfectos fisiológicos