Marty, F. M.Man, C. Y.Van der Horst, C.Francois, B.Garot, D.Mánez, R.Thamlikitkul, V.Lorente Balanza, José ÁngelÁlvarez Lerma, FranciscoBrealey, D.Zhao, H. H.Weller, S.Yates, P. J.Peppercorn, A. F.2015-07-172015-07-172014Marty, F. M., Man, C. Y., van der Horst, C., Francois, B., Garot, D., Máňez, R., ... & Peppercorn, A. F. (2014). Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study. Journal of Infectious Diseases, 209(4), 542-50.0022189915376613http://hdl.handle.net/11268/4210Intravenous zanamivir is a neuraminidase inhibitor suitable for treatment of hospitalized patients with severe influenza. Patients were treated with intravenous zanamivir 600 mg twice daily, adjusted for renal impairment, for up to 10 days. Primary outcomes included adverse events (AEs), and clinical/laboratory parameters. Pharmacokinetics, viral load, and disease course were also assessed.spaZanamivirjournal article10.1093/infdis/jit467open accessMedicamentosInvestigación médica