García Bonillo, CristinaLópez Lisbona, RosaDíez Ferrer, MartaMartí, SaraGilabert, JoanCubero, NoeliaSantos, SaludBorrós, SalvadorRossell, AntoniTexido, Robert2026-09-042026-09-042026Garcia-Bonillo, C., López-Lisbona, R., Díez-Ferrer, M., Marti, S., Gilabert, J., Cubero, N., Santos, S., Borrós, S., Rosell, A., & Texidó, R. (2026). Nanostructured silver-coated silicone tracheal stents confer hybrid anti-biofilm activity in vivo. ACS Applied Bio Materials. https://doi.org/10.1021/acsabm.6c005912576-6422https://hdl.handle.net/11268/17403Bacterial colonization and biofilm formation remain major limitations of airway stenting, contributing to device obstruction and infection-related complications. Here, we translated to silicone tracheal stents a previously developed plasma-assisted micro/nanostructured silver interface designed to provide hybrid anti-biofilm activity through reduced bacterial adhesion and controlled silver release. The coated stents were characterized to confirm the generation of the nanostructured silver coating and were evaluated against Gram-positive and Gram-negative bacteria in vitro, followed by in vivo assessment in a miniature pig airway model.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/BiocienciasMateriales biocompatiblesEquipos y suministrosMateriales biomédicos y dentalesjournal article10.1021/acsabm.6c00591open accessSustancia bioquímicaBacteriaBioquímicaGoal 3: Ensure healthy lives and promote well-being for all at all ages