Fuertes Recuero, ManuelPablo Moreno, Juan Andrés deRevuelta, LuisCox, DebbyDebenham, JohnMorón Elorza, PabloPablo Moreno, Javier María deAtencia, Rebeca2026-01-102026-01-102025Fuertes-Recuero, M., De Pablo-Moreno, J. A., Revuelta, L., Cox, D., Debenham, J., Morón-Elorza, P., De Pablo-Moreno, J. M., & Atencia, R. (2025). Severe generalized tetanus in a chimpanzee (Pan troglodytes) under human care: A case report from the republic of congo. Veterinary Sciences, 13(1), 13. https://doi.org/10.3390/vetsci130100132306-7381https://hdl.handle.net/11268/16692Tetanus is a life-threatening neurological disease affecting vertebrate species, including primates. Here, we present a case of severe generalized tetanus in a juvenile male chimpanzee (Pan troglodytes) that was rescued from the illegal wildlife trade and admitted to a rehabilitation center in the Republic of Congo. Upon arrival, the chimpanzee presented with deep, contaminated constrictive wounds, trismus, generalized rigidity, and stimulusinduced tonic spasms accompanied by transient apnea, while remaining conscious. A presumptive clinical diagnosis was made, after which integrated care began immediately. This included meticulous wound debridement and irrigation, passive immunization with antitoxin, initiation of active immunization, metronidazole with adjunctive penicillin G, diazepam-based spasm control, multimodal analgesia, and low-stimulation nursing with oxygen supplementation, enteral nutrition, and temporary urinary catheterization. Aerobic wound culture yielded mixed flora, and a Gram stain of the feces showed large Grampositive rods with terminal spores. Hematology tests revealed leucopenia with neutropenia and severe thrombocytopenia. The spasms ceased by day 5, at which point the diazepam dose was reduced and oral intake was increased. By week 8, he had made a full clinical recovery and was successfully reintegrated into his group. This case supports the use of pragmatic, sanctuary-adapted protocols and systematic vaccination.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal article10.3390/vetsci13010013open accessVeterinariaZoologíaEnfermedades infecciosasGoal 3: Ensure healthy lives and promote well-being for all at all agesGoal 12: Ensure sustainable consumption and production patternsGoal 15: Sustainably manage forests, combat desertification, halt and reverse land degradation, halt biodiversity loss