Rodríguez de Santiago, EnriquePérez de la Iglesia, SandraFrutos, Diego deMarin Gabriel, José CarlosMangas Sanjuan, CarolinaHonrubia López, RaúlUchima, HugoAicart Ramos, MartaRodríguez Gandía, Miguel ÁngelValdivielso Cortázar, EduardoEt.al.2025-06-242025-06-242025Rodríguez De Santiago, E., Pérez De La Iglesia, S., De Frutos, D., Marín-Gabriel, J. C., Mangas-SanJuan, C., Honrubia López, R., Uchima, H., Aicart-Ramos, M., Rodríguez Gandía, M. Á., Valdivielso Cortázar, E., Ramos Zabala, F., Álvarez, M. A., Solano Sánchez, M., González Santiago, J. M., Albéniz, E., Hijos-Mallada, G., Castro Quismondo, N., Fraile-López, M., Martínez Ares, D., … Pellisé, M. (2025). Delphi consensus statement for the management of delayed post-polypectomy bleeding. Therapeutic Advances in Gastroenterology, 18, 17562848251329145. https://doi.org/10.1177/175628482513291451756-2848http://hdl.handle.net/11268/14691Delayed post-polypectomy bleeding (DPPB) is the most common adverse event following colonic polypectomy, yet its management remains highly heterogeneous and lacks standardization. A considerable number of colonoscopies performed for DPPB may be unnecessary and do not result in hemostatic intervention. Objectives: To develop evidence-based statements to guide clinical decision-making in DPPB. Design: Multidisciplinary Delphi consensus statement. Methods: A panel of 29 experts in gastroenterology, hematology, radiology, and surgery was assembled. Through a systematic review of the literature and a modified Delphi process, consensus statements were developed through iterative rounds of anonymous voting. Statements were revised following anonymous voting and feedback at each round. Those achieving 80% agreement were accepted. Results: The expert panel reached a consensus on 36 statements, covering areas such as antithrombotic management, bowel preparation, colonoscopy indications, and therapeutic hemostatic modalities. Key recommendations include guidance for managing self-limited bleeding and risk stratification to reduce the rate of unnecessary colonoscopies, as well as recommendations for hemodynamically unstable patients who may require primary angioembolization. A practical clinical algorithm is proposed. Conclusion: This document provides a consensus-based framework for managing DPPB. These recommendations aim to improve patient outcomes and optimize healthcare resources while fostering a standardized approach to this common adverse event.engAtribución-NoComercial 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc/4.0/ColonoscopiaPólipos del colonExpectativas del tratamientojournal article10.1177/17562848251329145open accessInvestigación médicaEnfermedadCáncerGoal 3: Ensure healthy lives and promote well-being for all at all ages