Lucía Mulas, AlejandroÁvila Silván, M.López Mojares, Luis MiguelBoraita, AraceliPérez Ruiz, MargaritaFoster, CarlGarcía-Castro, J.Ramírez, Manuel2013-11-272013-11-272009Lucía-Mulas, A., Ávila-Silván, M., López-Mojares, L. M., Boraita, A., Pérez-Ruiz, M., Foster, C., ..., & Ramírez, M. (2009). Mobilisation of mesenchymal cells in cardiac patients: is intense exercise necessary? British Journal of Sports Medicine, 43(3), 214730480http://hdl.handle.net/11268/403Circulating mesenchymal cells (cMCs) have a potential for regenerating damaged tissue, e.g., ischaemic myocardium. In patients (age range: 53-76 years) with stable coronary artery disease cMCs were determined before and after dynamic exercise of moderate (RCT) (n = 11). Only high-intensity exercise (i.e., provoking signs of myocardial ischaemia in 3 patients and ventricular extrasystoles in another) induced a significant increase in cMCs (p = 0.009). These results support the hypothesis that intense exercise (near or at the point of myocardial ischaemia) is a potent stimulus for MC mobilisation.engCell Movement*Coronary Artery Disease/*RehabilitationExercise Therapy/*MethodsMesenchymal Stem Cells/*PhysiologyFlow CytometryHumansMaleMiddle AgedTreatment Outcomejournal article10.1136/bjsm.2007.044693restricted accessEnfermedad cardiovascularTratamiento médico