Differential contribution of T-type voltage-gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits

Suárez, AndreaGuerra Ojeda, SolZarzoso, ManuelSerna García, MartaVila, José ManuelSerna, EvaMauricio, María Dolores2026-02-192026-02-192025Suarez, A., Guerra‐Ojeda, S., Zarzoso, M., Serna‐García, M., Vila, J. M., Serna, E., & Mauricio, M. D. (2025). Differential contribution of T‐type voltage‐gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbits. Experimental Physiology, EP093044. https://doi.org/10.1113/EP0930440958-06701469-445Xhttps://hdl.handle.net/11268/16848T-type voltage-gated calcium channels (VGCCs) are comparatively understudied in large conduit artery function relative to the well-characterized L-type channel subtype. This study investigates the vascular roles of T-type VGCCs in the aorta and renal artery of healthy rabbits using functional reactivity assays and immunofluorescence and further elucidates the interaction between T-type VGCC activity and the nitric oxide (NO) signalling pathway.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/AortaEndotelioArteria renalDifferential contribution of T-type voltage-gated calcium channels to vascular reactivity in the aorta and renal artery of healthy rabbitsjournal article10.1113/EP093044open accessSistema cardiovascularInvestigación biológicaMedicina preventivaGoal 3: Ensure healthy lives and promote well-being for all at all ages