Ferruelo, AntonioLas Heras Alonso, Marta MireyaRedondo, CristinaFata Chillón, Fernando Ramón deRomero Cagigal, IgnacioAngulo Cuesta, Javier2015-07-232015-07-232014Ferruelo, A., de Las Heras, M. M., Redondo, C., de Fata, F. R., Romero, I., & Angulo, J. C. (2014). Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-κβ. Actas Urológicas Españolas (English Edition), 38(7), 429-437.0210480616797980http://hdl.handle.net/11268/4235Mediterranean diet may play a role in the prevention of prostate cancer (PCa) development and progression. Cyclooxygenase-2 (COX-2) expression is associated with increased cellular proliferation, prevents apoptosis and favors tumor invasion. We intend to clarify whether resveratrol and other polyphenols effectively inhibit COX-2 activity and induce apoptosis in hormone-resistant PC-3 cell line.engCáncer de próstata resistente a castraciónLínea celular PC-3Wine polyphenols exert antineoplasic effect on androgen resistant PC-3 cell line through the inhibition of the transcriptional activity of COX-2 promoter mediated by NF-κβLos polifenoles del vino ejercen su efecto antineoplásico sobre la línea celular PC-3 andrógeno resistente a través de la inhibición de la actividad transcripcional del promotor de COX-2 mediada por NF-κβjournal article10.1016/j.acuroe.2014.06.004restricted accessUrologiaCáncer