San Juan, Alejandro F.Gómez Gallego, FélixCañete, SilviaSantiago Dorrego, CatalinaPérez Ruiz, MargaritaLucía Mulas, Alejandro2016-08-082016-08-082006San Juan, A. F., Gómez-Gallego, F., Cañete, S., Santiago, C., Pérez, M., & Lucía, A. (2006). Does complete deficiency of muscle α actinin 3 alter functional capacity in elderly women? A preliminary report. British journal of sports medicine, 40(1), e1-e3.0306367414730480http://hdl.handle.net/11268/5580The sarcomeric protein α actinin 3 is localised to the Z line of fast fibres, which are responsible for generating forceful muscle contractions at high velocity. However, a substantial proportion of healthy humans are totally deficient in this protein as they are homozygous for a premature stop codon polymorphism (R577X) in the ACTN3 gene. The purpose of this preliminary study was to assess if the presence or absence of α actinin 3 influences the deleterious effects of ageing on muscle output and functional capacity.engjournal article10.1136/bjsm.2005.019539open accessProteínasCondición físicaProteínaDeporte