Rubia Ortí, José Enrique de laGarcía Pardo, María PilarCabañés Iranzo, CarmenCerón Madrigal, José JoaquínSancho Castillo, SandraRochina, Mariano JuliánPrado Gascó, Vicente Javier2018-07-042018-07-042018Rubia Ortí, J. E., García-Pardo, M. P., Iranzo, C. C., Madrigal, J. J. C., Castillo, S. S., Rochína, M. J., & Gascó, V. J. P. (2018). Does Music Therapy Improve Anxiety and Depression in Alzheimer's Patients? The Journal of Alternative and Complementary Medicine, 24(1), 33-36. DOI:10.1089/acm.2016.03461075-55351557-7708http://hdl.handle.net/11268/7331OBJECTIVE: To evaluate the effectiveness of the implementation of a short protocol of music therapy as a tool to reduce stress and improve the emotional state in patients with mild Alzheimer's disease. METHODS: A sample of 25 patients with mild Alzheimer's received therapy based on the application of a music therapy session lasting 60 min. Before and after the therapy, patient saliva was collected to quantify the level of salivary cortisol using the Enzyme-Linked ImmunoSorbent Assay (ELISA) immunoassay technique and a questionnaire was completed to measure anxiety and depression (Hospital Anxiety and Depression Scale). RESULTS: The results show that the application of this therapy lowers the level of stress and decreases significantly depression and anxiety, establishing a linear correlation between the variation of these variables and the variation of cortisol. CONCLUSIONS: A short protocol of music therapy can be an alternative medicine to improve emotional variables in Alzheimer patients.engjournal article10.1089/acm.2016.0346restricted accessAlzheimer, Enfermedad deTerapéuticaTerapiaMúsicaEnfermedad del sistema nerviosoEnfermedad mental