TY - JOUR A1 - Sinclair, Alan J. AU - Abdelhafiz, Ahmed H. AU - Rodríguez Mañas, Leocadio T1 - Frailty and sarcopenia - newly emerging and high impact complications of diabetes Y1 - 2017 SN - 1056-8727 UR - http://hdl.handle.net/11268/8811 AB - Diabetes increases the risk of physical dysfunction and disability. Diabetes-related complications and coexisting morbidities partially explain the deterioration in physical function. The decline in muscle mass, strength and function associated with diabetes leads to sarcopenia, frailty and eventually disability. Frailty acts as a mediator in the pathogenesis of disability in older people with diabetes and its measurement in routine daily practice is recommended. Frailty is a dynamic process which progresses from a robust condition to a pre-frail stage then frailty and eventually disability. Therefore, a multimodal intervention which includes adequate nutrition, exercise training, good glycaemic control and the use of appropriate hypoglycemic medications may help delay or prevent the progression to disability. KW - Diabetes en ancianos KW - Calidad de vida KW - Sistema endocrino KW - Anciano KW - Calidad de vida LA - spa ER -