TY - JOUR 
A1 - Brea Alejo, Lidia
AU - Pagola Aldazabal, Itziar
AU - Fiuza Luces, María del Carmen
AU - Huerga, Daniel
AU - Torres, María Victoria de
AU - Soria, Ana
AU - Ortega, María Jesús
AU - Felipe Hernández, José Luis
AU - Lucía Mulas, Alejandro
AU - Ruiz-Casado, Ana
T1 - Exercise prehabilitation program for patients under neoadjuvant treatment for rectal cancer: A pilot study
Y1 - 2019
SN - 0973-1482

UR - http://hdl.handle.net/11268/8017
AB - Context: Prehabilitation is emerging as a method of preparing patients physically and mentally for the often disabling effects of cancer treatment. 
Aims: This study aims to assess the feasibility and to explore the potential effects of a prehabilitation program consisting of educational physical exercise sessions in patients with rectal cancer undergoing neoadjuvant chemoradiotherapy treatment (NCRT). 
Settings and Design: This was a pilot study with 12 patients (3 males and 9 females, age 61 ± 7 years). 
Subjects and Methods: The program included six educational sessions of exercise during NCRT. Adherence to the intervention; quality of life (QoL); anxiety and depression; body mass index; physical fitness (peak oxygen uptake (VO2peak), handgrip and dynamic leg strength); and physical activity (PA) levels were measured. 
Statistical Analysis Used: Data are reported as the mean ± standard deviation or medians and interquartile ranges for questionnaire-derived data. Secondary outcome measures were compared using the nonparametric Wilcoxon test. The threshold P value for significance was calculated after correction for multiple comparisons using the Bonferroni method. 
Results: Adherence to the program was 64 of 72 possible exercise education sessions completed, i.e., 89%. We detected a trend toward a significant improvement in VO2peak after the intervention (P = 0.015), together with reduced scores for both depression (P = 0.017) and the QoL domain “emotional function” (P = 0.027). Mean levels of moderate to vigorous PA tended to increase after the exercise program (P = 0.091). 
Conclusions: Exercise might be an effective prehabilitation strategy for surgery during the period of NCRT.
KW - Ejercicio físico
KW - Hospitalizados
KW - Cáncer
KW - Cáncer
KW - Deporte
KW - Tratamiento médico
LA - eng
ER -