TY - JOUR 
A1 - García Abellán, Javier
AU - Río, Lorena del
AU - García, José A.
AU - Padilla, Sergio
AU - Vivancos, María J.
AU - Romero, Jorge del
AU - Asensi, Víctor
AU - Hernando Jeréz, María Asunción
AU - García Fraile, Lucio
AU - Masiá, Mar
AU - Gutiérrez, Félix
T1 - Riesgo de cáncer en personas con VIH en España, 2004-2015. Estudio de la cohorte CoRIS

Y1 - 2019
SN - 0213-005X
UR - http://hdl.handle.net/11268/7864
AB - Introduction: Cancer is a leading cause of death in individuals with HIV.
Methods: The incidence of cancer in HIV patients of the CoRIS cohort in the 2004-2009 and 2010-2015
periods has been analysed and compared to the incidence in the Spanish general population, estimated
from data of the Spanish Cancer Registry Network.
Results: Between January 2004 and November 2015, 12,239 patients were included in CoRIS and 338
incident cancer cases were diagnosed. The overall incidence of cancer per 100,000 persons-year (95% CI)
was 702.39 (629.51-781.42) with no significant differences between the 2 periods. A 38% of the incident
cancer cases were AIDS defining cancers (ADC) and 62% non-AIDS defining cancers (NADC). In the period
2010-2015, there was a significant decrease in the incidence of ADC (standardised incidence ratio [SIR]);
95% CI: 0.38; 0.21-0.66) and NADC predominated. Compared to the general population, the incidence of
cancer was double in men with HIV. Higher relative risks were documented (SIR; 95% CI) for Hodgkin’s
lymphoma in both sexes (males: 8.37, 5.13-14.17; females: 21.83, 2.66-47.79), non-Hodgkin’s lymphoma
in males (5.30, 2.86-8.45) and cervical cancer (7.43, 3.15-13.87) and head and neck cancer (3.28, 1.21-5.82)
in women.
Conclusions: The overall incidence of cancer in individuals with HIV is higher than in the Spanish general
population, and it has remained stable since 2004 with a current predominance of NADC. These data
suggest that additional efforts should be made in the prevention and the early detection of cancer in
these patients.
KW - Cáncer
KW - SIDA
KW - Cáncer
KW - Sida
LA - spa
ER -