TY - JOUR 
A1 - Martínez López, María Ángeles
AU - García Puig, Juan
AU - Loeches, María P.
AU - Mateo, Maria C.
AU - Utiel, Isaías
AU - Torres, Rosa
T1 - Home blood pressure vs. clinic blood pressure measurement-based follow up in type II diabetics: Effect on 24-h ambulatory BP and albuminuria. Randomised trial


Y1 - 2018
SN - 0025-7753

UR - http://hdl.handle.net/11268/7345
AB - Bakground and objective:
To compare the efficacy of two strategies of blood pressure (BP) measurement-based follow-up in hypertension and albuminuria control.

Patients and methods:
Multicentre, prospective, randomized, open trial with a parallel-group design. Nineteen primary care centres and a hospital clinic participated. Adult type 2 diabetics with systolic BP ≥140 mmHg without relevant renal disease were randomized to one of two follow-up strategies: (1) standard follow up, with a clinic BP target <140/90 mmHg and (2) self-monitoring home BP (SMHBP)-based follow up, with a BP target <135/85 mmHg. Biochemical standard blood variables, albuminuria, and 24-h ambulatory BP monitoring were performed at entry, 12 and 24 months. The main outcome measurement was 24-h ambulatory systolic BP variation. Albuminuria change was analyzed as a secondary outcome.

Results:
116 patients were analyzed (mean age: 66.8 years). Mean systolic ambulatory 24-h BP change in two years was 3.9 mmHg (95% CI 1.8–6.1). We did not find significant differences between both groups (p = 0.706). Similarly, no differences were found when we compared other ambulatory BP values. Initial albuminuria was similar in both groups and did not significantly changed throughout the follow-up period.

Conclusion:
In type 2 diabetics without relevant nephropathy a SMHBP- based follow up was equivalent to a standard clinic-based BP follow up in BP and albuminuria control.

KW - Presión sanguínea
KW - Albuminuria
KW - Sistema cardiovascular
KW - Proteína
LA - eng
ER -