TY - JOUR 
A1 - Santiago Dorrego, Catalina
AU - Ruiz, Jonatan R.
AU - Muniesa Ferrero, Carlos Alberto
AU - González-Freire, Marta
AU - Gómez Gallego, Félix
AU - Lucía Mulas, Alejandro
T1 - Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing
Y1 - 2010
SN - 09057188
UR - http://hdl.handle.net/11268/664
AB - We determined whether the polygenic profile computed with seven candidate polymorphisms (i.e., ACE, ACTN3, AMPD1, CKMM, HFE, GDF-8 and PPARGC1A) for endurance performance is different in 39 world-class and 15 national-class Spanish (Caucasian) lightweight rowers. The second purpose was to examine the impact of possessing a "preferable" polygenic profile on the sport success in terms of the number of medals won in World and National Championships. Finally, we also compared the polygenic profile of world- and national-class Spanish rowers with that of the general Spanish population. The polygenic profile did not differ between groups of rowers. We did not observe an association between having a preferable polygenic profile and medals won in World and National Championships. Finally, we observed that rowers tend to have a more "favorable" polygenic profile than the general Spanish population. These findings argue against the idea that genetic endowment differentiates athletic champions from elite, yet less accomplished athletes. In contrast, we cannot discard the fact that, overall, elite athletes are endowed with a more "favorable" polygenic profile than the general population.
KW - Multifactorial Inheritance*
KW - Polymorphism, Genetic*
KW - Sports/*Physiology
KW - European Continental Ancestry Group/Genetics
KW - Genotype
KW - Humans
KW - Male
KW - Physical Endurance/Physiology
KW - Spain
KW - Genética humana
KW - Fisiología humana
KW - Atleta
LA - eng
ER -