TY - JOUR A1 - Pérez Ruiz, Margarita AU - Morán, María AU - Cardona González, Claudia Andrea AU - Maté-Muñoz, José Luis AU - Rubio, Juan Carlos AU - Andreu, Antoni L. AU - Martín, Miguel Ángel AU - Arenas, Joaquín AU - Lucía Mulas, Alejandro T1 - Can patients with McArdle’s disease run? Y1 - 2007 SN - 03063674 UR - http://hdl.handle.net/11268/5465 AB - Patients with McArdle's disease commonly adopt a sedentary lifestyle. This sedentary behaviour, however, usually worsens the limited exercise capacity of these patients. Although eccentric muscle work can be associated with rhabdomyolysis, supervised eccentric training with gradually increasing loads has important advantages compared with conventional concentric work, particularly for patients with a poor cardiorespiratory system. We report the beneficial effects (particularly, increased VO↓2peak (from 14.6 to 30.8 ml/kg/min) and increased gross muscle efficiency (from 13.8% to 17.2%)) induced by a supervised aerobic training programme of 7 months duration including 3–4 running sessions (⩽60 min/session) per week in a 38‐year‐old patient. These preliminary data suggest the potential therapeutic value of this type of exercise in these patients. KW - Enfermedades-McArdle KW - Condición física-Ejercicios KW - Metabolismo KW - Deporte LA - eng ER -