TY - JOUR A1 - Santodomingo Rubido, Jacinto AU - Villa Collar, César AU - Gilmartin, Bernard AU - Gutiérrez Ortega, Ángel Ramón AU - Suzaki, Asaki T1 - Short- and long-term changes in corneal aberrations and axial length induced by orthokeratology in children are not correlated Y1 - 2017 SN - 15422321 UR - http://hdl.handle.net/11268/5335 AB - The purpose of this study is to assess the correlation between changes in corneal aberrations and the 2-year change in axial length in children fitted with orthokeratology (OK) contact lenses. Thirty-one subjects 6 to 12 years of age and with myopia -0.75 to -4.00DS and astigmatism ≤1.00DC were fitted with OK. Measurements of axial length and corneal topography were taken at regular intervals over a 2-year period. Corneal topography at baseline and after 3 and 24 months of OK lens wear was used to derive higher-order corneal aberrations (HOA) that were correlated with OK-induced axial length changes at 2 years. Significant changes in C3, C4, C4, root mean square (RMS) secondary astigmatism and fourth and total HOA were found with both 3 and 24 months of OK lens wear in comparison with baseline (all P<0.05). Additionally, significant changes in C3 and RMS tetrafoil were found at 3 months and in second-order RMS at 24 months of OK lens wear in comparison with baseline (all P<0.05). However, none of the changes in corneal aberrations were significantly correlated with the 2-year change in axial elongation (all P>0.05). Coma angle of orientation changed significantly pre-OK in comparison with 3 and 24 months post-OK as well as secondary astigmatism angle of orientation pre-OK in comparison with 24 months post-OK (all P<0.05). However, coma, trefoil, secondary astigmatism, and tetrafoil angles of orientation pre-OK or post-OK were not significantly correlated with the 2-year change in axial elongation (all P>0.05). Short-term and long-term OK lens wear induces significant changes in corneal aberrations that are not significantly correlated with changes in axial elongation after 2-years. KW - Oftalmología pediátrica KW - Ojos - Enfermedades en niños KW - Oftalmología KW - Pediatría LA - eng ER -