TY - JOUR A1 - Cardinal Fernández, Pablo AU - Muñoz Rincón, D. A. AU - Thille, Arnaud W. AU - Jaramillo, C. AU - Ballén Barragán, A. AU - Herrero, Raquel AU - Nin, Nicolás AU - Cal, Miguel A. de la AU - Esteban, Andrés AU - Lorente Balanza, José Ángel T1 - Acute respiratory distress syndrome sub-phenotypes according to histological findings Y1 - 2014 SN - 03424642 UR - http://hdl.handle.net/11268/4207 AB - The objective is to demonstrate that among patients with the clinical diagnosis of ARDS, the presence of diffuse alveolar damage (DAD) at histological examination, as compared to its absence, defines a clinical sub-phenotype. We studied patients that died in our ICU from 2000 to 2012 with the diagnosis of ARDS according to the Berlin definition and had autopsy. We excluded patients dying [14 days after the diagnosis of ARDS. The diagnosis of DAD required the presence of hyaline membranes plus at least one of the following: intra-alveolar edema, alveolar type I cell necrosis, alveolar type II cell proliferation, interstitial proliferation of fibroblasts or organizing interstitial fibrosis. KW - Síndrome de dificultad respiratoria aguda KW - Aparato respiratorio KW - Aparato respiratorio LA - spa ER -