TY - JOUR A1 - Lucía Mulas, Alejandro AU - Ávila Silván, M. AU - López Mojares, Luis Miguel AU - Boraita, Araceli AU - Pérez Ruiz, Margarita AU - Foster, Carl AU - García-Castro, J. AU - Ramírez, Manuel T1 - Mobilisation of mesenchymal cells in cardiac patients: is intense exercise necessary? Y1 - 2009 SN - 14730480 UR - http://hdl.handle.net/11268/403 AB - Circulating mesenchymal cells (cMCs) have a potential for regenerating damaged tissue, e.g., ischaemic myocardium. In patients (age range: 53-76 years) with stable coronary artery disease cMCs were determined before and after dynamic exercise of moderate (RCT) (n = 11). Only high-intensity exercise (i.e., provoking signs of myocardial ischaemia in 3 patients and ventricular extrasystoles in another) induced a significant increase in cMCs (p = 0.009). These results support the hypothesis that intense exercise (near or at the point of myocardial ischaemia) is a potent stimulus for MC mobilisation. KW - Cell Movement* KW - Coronary Artery Disease/*Rehabilitation KW - Exercise Therapy/*Methods KW - Mesenchymal Stem Cells/*Physiology KW - Flow Cytometry KW - Humans KW - Male KW - Middle Aged KW - Treatment Outcome KW - Enfermedad cardiovascular KW - Tratamiento médico LA - eng ER -