TY - JOUR 
A1 - Santalla Hernández, Alfredo
AU - Munguía-Izquierdo, Diego
AU - Brea Alejo, Lidia
AU - Pagola Aldazabal, Itziar
AU - Díez Bermejo, Jorge
AU - Fleck, Steven J.
AU - Ara, Ignacio
AU - Lucía Mulas, Alejandro
T1 - Feasibility of resistance training in adult McArdle patients: clinical outcomes and muscle strength and mass benefits
Y1 - 2014
SN - 16634365
UR - http://hdl.handle.net/11268/4003
AB - We analyzed the effects of a 4-month resistance (weight lifting) training program followed by a 2-month detraining period in 7 adult McArdle patients (5 female) on: muscle mass (assessed by DXA), strength, serum creatine kinase (CK) activity and clinical severity. Adherence to training was ≥84% in all patients and no major contraindication or side effect was noted during the training or strength assessment sessions. The training program had a significant impact on total and lower extremities' lean mass (P < 0.05 for the time effect), with mean values increasing with training by +855 g (95% confidence interval (CI): 30, 1679) and +547 g (95%CI: 116, 978), respectively, and significantly decreasing with detraining.
KW - Rhabdomyolysis
KW - Muscle atrophy
KW - Muscle weakness
KW - Glycogenosis
KW - Enfermedades - McArdle
KW - Ejercicio físico
KW - Genética
KW - Salud
KW - Ciencia
LA - eng
ER -