TY - JOUR 
A1 - Castro Piñero, José
AU - Carbonell-Baeza, Ana
AU - Martínez-Gómez, David
AU - Gómez Martínez, Sonia
AU - Cabañas Sánchez, Verónica
AU - Santiago Dorrego, Catalina
AU - Veses, A. M.
AU - Bandrés Moya, Fernando
AU - González-Galo, A.
AU - Gómez Gallego, Félix
AU - Veiga, Óscar Luis
AU - Ruiz, Jonatan R.
AU - Marcos, Ascensión
T1 - Follow-up in healthy schoolchildren and in adolescents with DOWN syndrome: psycho-environmental and genetic determinants of physical activity and its impact on fitness, cardiovascular diseases, inflammatory biomarkers and mental health; the UP&DOWN Study.
Y1 - 2014
SN - 14712458
UR - http://hdl.handle.net/11268/2947
AB - BACKGROUND: An objective diagnosis of sedentary behaviour as well as of the physical activity and fitness levels in youth and to better understand how lifestyle is associated with cardiovascular disease risk factors and other phenotypes is of clinical and public health interest, and might be informative for developing intervention studies focused on the promotion of physical activity in these population. The aim of this methodological paper is to describe the design and assessment in the UP&DOWN study.
METHODS: The UP&DOWN study is a multi-center follow-up design where 2225 Spanish primary and secondary schoolchildren from Cadiz and Madrid, respectively, as well as 110 Spanish adolescents with Down syndrome from Madrid and Toledo were recruited to be assessed. Nine main measurement categories are assessed: i) socio-demographic and early determinants; ii) environmental determinants; iii) physical activity and sedentary behaviour; iv) health-related fitness; v) blood pressure and resting heart rate; vi) mental health; vii) dietary patterns; viii) blood samples; and ix) genetic analysis. During the 3-yr follow-up study, socio-demographic and early determinants, and genetic analysis are only assessed in the first year. Blood sampling is assessed in the first year and the third year (2nd follow-up), and all the other measurements are assessed every year.
DISCUSSION: The findings of the UP&DOWN study may help the Health Information Systems and policy makers to identify the target population for primary prevention and health promotion policies, and to develop and test preventive strategies. Moreover, these data will allow following the trends at population level, as well as to modify/adapt/create new evidence-based physical activity guidelines at national level. The findings will also serve as a scientific platform for interventional studies
KW - Deportes y recreación
KW - Educación física - enseñanza
KW - Educación física
LA - eng
ER -