TY - JOUR 
A1 - González Martínez, Silvia
AU - Pizarro, David
AU - Pérez Mies, Belén
AU - Caniego Casas, Tamara
AU - Curigliano, Giuseppe
AU - Cortés Castán, Javier
AU - Palacios, José
T1 - Clinical, Pathological, and Molecular Features of Breast Carcinoma Cutaneous Metastasis
Y1 - 2021
SN - 2072-6694
UR - http://hdl.handle.net/11268/11375
AB - Cutaneous metastases (CMs) account for 2% of all skin malignancies, and nearly 70% of CMs in women originate from breast cancer (BC). CMs are usually associated with poor prognosis, are difficult to treat, and can pose diagnostic problems, such as in histopathological diagnosis when occurring long after development of the primary tumor. In addition, the molecular differences between the primary tumors and their CMs, and between CMs and metastases in other organs, are not well defined. Here, we review the main clinical, pathological, and molecular characteristics of breast cancer CMs. Identifying molecular markers in primary BC that predict CM and can be used to determine the molecular differences between primary tumors and their metastases is of great interest for the design of new therapeutic approaches.
KW - Neoplasias de la mama
KW - Neoplasias cutáneas
KW - Metástasis de la neoplasia
KW - Cáncer
KW - Medicina preventiva
KW - Tecnología médica
LA - eng
ER -