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dc.contributor.author | García Abellán, Javier | |
dc.contributor.author | Río, Lorena del | |
dc.contributor.author | García, José A. | |
dc.contributor.author | Padilla, Sergio | |
dc.contributor.author | Vivancos, María J. | |
dc.contributor.author | Romero, Jorge del | |
dc.contributor.author | Asensi, Víctor | |
dc.contributor.author | Hernando Jeréz, María Asunción | |
dc.contributor.author | García Fraile, Lucio | |
dc.contributor.author | Masiá, Mar | |
dc.contributor.author | Gutiérrez, Félix | |
dc.date.accessioned | 2019-05-07T14:50:40Z | |
dc.date.available | 2019-05-07T14:50:40Z | |
dc.date.issued | 2019 | |
dc.identifier.citation | García-Abellán, J., del Río, L., García, J. A., Padilla, S., Vivancos, M. J., del Romero, J., ... y Gutiérrez, F. (2019). Riesgo de cáncer en personas con VIH en España, 2004-2015. Estudio de la cohorte CoRIS. Enfermedades Infecciosas y Microbiología Clínica, 37(8), 502-508. https://doi.org/10.1016/j.eimc.2018.11.011 | spa |
dc.identifier.issn | 0213-005X | |
dc.identifier.uri | http://hdl.handle.net/11268/7864 | |
dc.description.abstract | Introduction: Cancer is a leading cause of death in individuals with HIV. Methods: The incidence of cancer in HIV patients of the CoRIS cohort in the 2004-2009 and 2010-2015 periods has been analysed and compared to the incidence in the Spanish general population, estimated from data of the Spanish Cancer Registry Network. Results: Between January 2004 and November 2015, 12,239 patients were included in CoRIS and 338 incident cancer cases were diagnosed. The overall incidence of cancer per 100,000 persons-year (95% CI) was 702.39 (629.51-781.42) with no significant differences between the 2 periods. A 38% of the incident cancer cases were AIDS defining cancers (ADC) and 62% non-AIDS defining cancers (NADC). In the period 2010-2015, there was a significant decrease in the incidence of ADC (standardised incidence ratio [SIR]); 95% CI: 0.38; 0.21-0.66) and NADC predominated. Compared to the general population, the incidence of cancer was double in men with HIV. Higher relative risks were documented (SIR; 95% CI) for Hodgkin’s lymphoma in both sexes (males: 8.37, 5.13-14.17; females: 21.83, 2.66-47.79), non-Hodgkin’s lymphoma in males (5.30, 2.86-8.45) and cervical cancer (7.43, 3.15-13.87) and head and neck cancer (3.28, 1.21-5.82) in women. Conclusions: The overall incidence of cancer in individuals with HIV is higher than in the Spanish general population, and it has remained stable since 2004 with a current predominance of NADC. These data suggest that additional efforts should be made in the prevention and the early detection of cancer in these patients. | spa |
dc.description.sponsorship | La cohorte RIS (CoRIS) está financiada por el ISCIII a través de la Red Temática de Investigación Cooperativa en Sida (RD06/0006/0027; RD12/0017/0023 y RD16/0025/0038) como parte del Plan Nacional de I + D + I, cofinanciado por el Fondo Europeo de Desarrollo Regional (FEDER). Los autores de este trabajo han recibido financiación del ISCIII-Plan Nacional de I + D + I(FIS: PI08/893, PI13/02256, PI16/01740, PI18/01861; contrato de intensificación de la actividad investigadora INT 14/00207; contrato Río Hortega CM15/00187) y de FISABIO (UGP-14-197 y contrato predoctoral UGP-15-152). | spa |
dc.language.iso | spa | spa |
dc.title | Riesgo de cáncer en personas con VIH en España, 2004-2015. Estudio de la cohorte CoRIS | spa |
dc.title.alternative | Risk of cancer in HIV-infected patients in Spain, 2004-2015. The CoRIS cohort study | spa |
dc.type | article | spa |
dc.description.impact | 1.654 JCR (2019) Q4, 79/93 Infectious Diseases, 112/135 Microbiology | spa |
dc.description.impact | 0.317 SJR (2019) Q3, 83/128 Microbiology (medical) | spa |
dc.description.impact | No data IDR 2019 | spa |
dc.identifier.doi | 10.1016/j.eimc.2018.11.011 | |
dc.rights.accessRights | closedAccess | spa |
dc.subject.uem | Cáncer | spa |
dc.subject.uem | SIDA | spa |
dc.subject.unesco | Cáncer | spa |
dc.subject.unesco | Sida | spa |
dc.description.filiation | UEM | spa |
dc.peerreviewed | Si | spa |
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