Mostrar el registro sencillo del ítem
dc.contributor.author | Clemente Suárez, Vicente Javier | |
dc.contributor.author | Mielgo Ayuso, Juan | |
dc.contributor.author | Quiles Morales, José Luís | |
dc.contributor.author | Varela López, Alfonso | |
dc.contributor.author | Aranda Ramírez, Pilar | |
dc.date.accessioned | 2018-11-27T18:08:01Z | |
dc.date.available | 2018-11-27T18:08:01Z | |
dc.date.issued | 2017 | |
dc.identifier.citation | Clemente-Suárez, V. J., Mielgo-Ayuso, J., Quiles, J. L., Varela-Lopez, A., & Aranda, P. (2017). Effect of α-tocopherol megadoses on hematologic parameters and antioxidant capacity of rats in an ultraendurance probe. Physiology international, 104(4), 291-300. https://dx.doi.org/10.1556/2060.104.2017.4.2 | spa |
dc.identifier.issn | 2498-602X | |
dc.identifier.uri | http://hdl.handle.net/11268/7628 | |
dc.description.abstract | This study was aimed to analyze the effect of two different megadoses of α-tocopherol (vit E) in the antioxidant activity and red and white blood series of Wistar rats after a 180-min ultraendurance probe. Three groups of 10 rats were analyzed; VEAG: acute administration of a megadoses of 5,000 IU/kg of vit E the day before the probe; VECG: chronic administration of 1,000 IU/kg/day of vit E for 6 days before the probe; CG: placebo administration. VEAG presented white cells, red blood cells, hematocrit, hemoglobin values significantly higher than CG and VECG (p < 0.05). The mean corpuscular hemoglobin and lymphocytes concentrations were significantly higher in the VECG than in the other two groups (p < 0.05). Similarly, VEAG presented a significantly higher vit E blood concentration than VECG and CG (p < 0.05), and VECG than CG (p < 0.05). Finally, we found a significantly positive correlation between trolox equivalent antioxidant capacity (TEAC) and red blood cells concentration (r = 0.374) and a significantly inverse correlation between TEAC and blood lactate concentration (r = −0.365). Our findings suggest that acute vit E megadoses could protect against transitory sport anemia symptoms and increase the white blood cell count in comparison with the chronic dose and control groups after an ultraendurance probe. | spa |
dc.description.sponsorship | 2016/UEM26 | spa |
dc.language.iso | eng | spa |
dc.title | Effect of α-tocopherol megadoses on hematologic parameters and antioxidant capacity | spa |
dc.type | article | spa |
dc.description.impact | 0.558 JCR (2017) Q4, 78/83 Physiology | spa |
dc.description.impact | 0.256 SJR (2017) Q4, 84/107 Physiology (medical) | spa |
dc.description.impact | No data IDR 2017 | spa |
dc.identifier.doi | 10.1556/2060.104.2017.4.2 | |
dc.rights.accessRights | closedAccess | spa |
dc.subject.uem | Antioxidantes | spa |
dc.subject.uem | Hematología | spa |
dc.subject.uem | Vitamina E | spa |
dc.subject.unesco | Vitamina | spa |
dc.subject.unesco | Investigación | spa |
dc.subject.unesco | Desarrollo fisiológico | spa |
dc.description.filiation | UEM | spa |
dc.peerreviewed | Si | spa |
Ficheros | Tamaño | Formato | Ver |
---|---|---|---|
No hay ficheros asociados a este ítem. |