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dc.contributor.author | Gómez Gallego, Félix | spa |
dc.contributor.author | Ruiz, Jonatan R. | spa |
dc.contributor.author | Buxens, Amaya | spa |
dc.contributor.author | Artieda, Marta | spa |
dc.contributor.author | Arteta, David | spa |
dc.contributor.author | Santiago Dorrego, Catalina | spa |
dc.contributor.author | Rodríguez Romo, Gabriel | spa |
dc.contributor.author | Lao, José I. | spa |
dc.contributor.author | Lucía Mulas, Alejandro | spa |
dc.date.accessioned | 2013-11-27T17:26:28Z | |
dc.date.available | 2013-11-27T17:26:28Z | |
dc.date.issued | 2009 | spa |
dc.identifier.citation | González-Freire, M., Santiago-Dorrego, C., Verde-Rello, Z., Lao, J. I., Olivan-Mallen, J., Gómez-Gallego, F., & Lucía-Mulas, A. (2009). Unique among unique: is it genetically determined? British Journal of Sports Medicine, 43(4), 307-309. | spa |
dc.identifier.issn | 14396327 | spa |
dc.identifier.uri | http://hdl.handle.net/11268/754 | |
dc.description.abstract | The NOS3 gene is a candidate to explain individual variations in health and exercise related phenotypes. We compared genotypic and allelic frequencies of the NOS3 -786 T/C polymorphism (rs2070744) in three groups of men of the same Caucasian (Spanish) descent: (i) elite endurance athletes (cyclists, runners; N = 100); (ii) elite power athletes (jumpers, throwers, sprinters; N = 53) and (iii) non-athletic controls (N = 100). The frequency of the TT genotype was significantly higher in power athletes (57%) than in the endurance (33%, P = 0.017) or control group (34%, P = 0.026). The frequency of the T allele was also higher in power sportsmen (71%) than in their endurance (55%, P = 0.003) and control referents (56%, P = 0.015). No differences were observed between control and endurance groups. In summary, the -786 T/C polymorphism of the NOS3 gene seems to be associated with elite performance in power-oriented athletic events (throwing, jumping, sprinting), with the T allele exerting a beneficial effect. The mechanism by which this allele variant might benefit power performance remains to be elucidated. | spa |
dc.language.iso | eng | spa |
dc.title | The -786 T/C polymorphism of the NOS3 gene is associated with elite performance in power sports | spa |
dc.type | article | spa |
dc.description.impact | 2.047 JCR (2009) Q1, 16/73 Sport sciences; Q3, 40/75 Physiology | spa |
dc.identifier.doi | 10.1007/s00421-009-1166-7 | spa |
dc.rights.accessRights | openAccess | en |
dc.subject.unesco | Genética humana | spa |
dc.subject.unesco | Atleta | spa |
dc.description.filiation | UEM | spa |
dc.peerreviewed | Si | spa |
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