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dc.contributor.author | Muñoz, Patricia | |
dc.contributor.author | Vena, Antonio | |
dc.contributor.author | Cerón, Inés | |
dc.contributor.author | Valerio Minero, Maricela | |
dc.contributor.author | Palomo, Jesús | |
dc.contributor.author | Guinea, Jesús | |
dc.contributor.author | Escribano Subías, Pilar | |
dc.contributor.author | Martínez Sellés Oliveria Soares, Manuel | |
dc.contributor.author | Bouza, Emilio | |
dc.date.accessioned | 2015-06-17T15:12:09Z | |
dc.date.available | 2015-06-17T15:12:09Z | |
dc.date.issued | 2014 | |
dc.identifier.citation | Muñoz, P., Vena, A., Cerón, I., Valerio, M., Palomo, J., Guinea, J., ..., & Bouza, E. (2014). Invasive pulmonary aspergillosis in heart transplant recipients: two radiologic patterns with a different prognosis. The Journal of Heart and Lung Transplantation, 33(10), 1034-1040. | spa |
dc.identifier.issn | 10532498 | |
dc.identifier.uri | http://hdl.handle.net/11268/4018 | |
dc.description.abstract | Background Computed tomography (CT) findings can be used to classify invasive pulmonary aspergillosis (IPA) in 2 patterns: airway-invasive (AIR) or angioinvasive (ANG). Methods AIR-IPA was considered when the CT revealed peribronchial consolidation or a tree-in-bud pattern and ANG-IPA when a nodule, cavity, halo sign, infarct-shaped, or mass-like consolidation was found. We evaluated the correlation among IPA patterns on CT and outcomes in heart transplant (HT) recipients. Results The study included 27 HT recipients with a CT scan performed at the time of IPA diagnosis. The study interval was from 1988 to 2011. Ten AIR-IPA patients (37.1%) were compared with 17 ANG-IPA patients (62.9%). During the post-transplantation period before IPA developed, AIR patients required hemodialysis more frequently (40% vs 5.9%, p = 0.04). AIR patients also had more intercurrent bacterial pneumonia (23.5% vs 70%, p < 0.001), and IPA was diagnosed later after onset of symptoms (2.7 vs 8.5 d, p = 0.09). After diagnosis, AIR-IPA patients required more mechanical ventilation (23.5% vs 90%, p < 0.01) and had a higher related mortality rate (23.5% vs 70%, p = 0.04). Conclusions Our study shows that the AIR pattern represents 37% of IPA episodes in HT recipients and is associated with a more protracted clinical presentation, later diagnosis, and higher mortality rate. | spa |
dc.language.iso | eng | spa |
dc.subject.other | Aspergillosis invasiva | spa |
dc.subject.other | Trasplante de corazón | spa |
dc.title | Invasive pulmonary aspergillosis in heart transplant recipients: two radiologic patterns with a different prognosis | spa |
dc.type | article | spa |
dc.description.impact | 6.650 JCR (2014) Q1, 9/123 Cardiac & cardiovascular systems, 6/57 Respiratory system, 3/198 Surgery, 1/25 Transplantation | spa |
dc.identifier.doi | 10.1016/j.healun.2014.05.003 | spa |
dc.rights.accessRights | closedAccess | spa |
dc.subject.uem | Cardiología | spa |
dc.subject.uem | Pulmones - Enfermedades | spa |
dc.subject.unesco | Aparato respiratorio | spa |
dc.subject.unesco | Sistema cardiovascular | spa |
dc.subject.unesco | Enfermedad | spa |
dc.description.filiation | UEM | spa |
dc.peerreviewed | Si | spa |
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