Abstract:
González-Hernández, JM, Jiménez-Reyes, P, Cerón, JJ, Tvarijonaviciute, A, Llorente-Canterano, FJ, Martínez-Aranda, LM, and García-Ramos, A. Response of muscle damage markers to an accentuated eccentric training protocol: do serum and saliva measurements agree? J Strength Cond Res XX(X): 000-000, 2020-This study aimed (a) to examine the acute and delayed responses of 3 muscle damage biomarkers: creatine kinase (CK), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH) to an accentuated eccentric training protocol in serum, and (b) to explore the changes of these biomarkers in saliva and compare them with serum. Sixteen resistance-trained university students (10 men [age = 26.6 ± 4.8 years, full squat one repetition maximum [1RM] = 103.4 ± 14.4 kg] and 6 women [age = 22.7 ± 1.4 years, full squat estimated 1RM = 68.3 ± 10.5 kg]) completed an accentuated eccentric strength training protocol with the full squat exercise consisting of 8 sets of 10 repetitions against the 120% estimated 1RM load with 5 minutes of interset rest. The activity of muscle damage biomarkers (CK, AST, and LDH) was measured in serum and saliva before training (Pre), 24 hours after training (Post24), and 96 hours af...